{"id":204,"date":"2023-03-28T23:03:20","date_gmt":"2023-03-29T04:03:20","guid":{"rendered":"https:\/\/coco66.com\/study-finds-pre-vaccination-expectations-linked-to-adverse-events-in-covid-19-vaccination-highlights-importance-of-contextualizing-vaccine-information-and-treatment-with-nirmatrelvir-in-acute-phase\/"},"modified":"2023-03-28T23:03:20","modified_gmt":"2023-03-29T04:03:20","slug":"study-finds-pre-vaccination-expectations-linked-to-adverse-events-in-covid-19-vaccination-highlights-importance-of-contextualizing-vaccine-information-and-treatment-with-nirmatrelvir-in-acute-phase","status":"publish","type":"post","link":"https:\/\/coco66.com\/study-finds-pre-vaccination-expectations-linked-to-adverse-events-in-covid-19-vaccination-highlights-importance-of-contextualizing-vaccine-information-and-treatment-with-nirmatrelvir-in-acute-phase\/","title":{"rendered":"Study Finds Pre-Vaccination Expectations Linked to Adverse Events in COVID-19 Vaccination, Highlights Importance of Contextualizing Vaccine Information and Treatment with Nirmatrelvir in Acute Phase"},"content":{"rendered":"

A recent study published in JAMA Network Open explored the relationship between pre-vaccination expectations and systemic adverse events among individuals receiving their second dose of a COVID-19 vaccine.[0]<\/a><\/sup> The study found that expectations of low benefit, high adverse effects, and prior negative experiences were associated with COVID-19 vaccination adverse effects. Additionally, the tendency to catastrophize instead of normalize benign bodily sensations was also linked to higher reported adverse events.[1]<\/a><\/sup> The authors of the study suggest that these insights could be beneficial for clinician-patient interactions and public vaccine campaigns by optimizing and contextualizing information provided about COVID-19 vaccines. <\/p>\n

One significant contributor to vaccine hesitancy has been concerns about adverse events.[2]<\/a><\/sup> The study concluded that the severity and frequency of systemic adverse events in the week after COVID-19 vaccination “was not only caused by vaccine-specific reactogenicity but also by psychosocial context factors that can be identified prior to vaccination.”[2]<\/a><\/sup> The three major contributors to nocebo effects included personal prior reactions to the first COVID-19 vaccination, individual expectations regarding potential harms and benefits of vaccination, and symptom misattribution. <\/p>\n

The study also found that having excellent knowledge about the COVID-19 vaccine was significantly associated with a positive practice of vaccinating children between ages 12 and 18 years with the COVID-19 vaccine. The researchers noted that clinicians and public vaccine campaigns could benefit from contextualizing information about COVID-19 vaccines and being transparent about their risk-benefit profiles to improve overall vaccine acceptance. <\/p>\n

The efficacy of COVID-19 vaccines in curbing infection, morbidity, and mortality, including against the latest COVID-19 strains, is well-established. However, their effectiveness hinges on a substantial portion of the population receiving vaccination. A recent study reported that vaccination has reduced the risk of developing long COVID-19 symptoms caused by the SARS-CoV-2 virus. <\/p>\n

The study also explored the response to vaccination of recovered COVID-19 patients and found that their SARS-CoV-2-specific response to vaccination lagged behind that of never-infected participants\u2019 response. The study found that uninfected vaccine recipients experienced a greater than 60-fold rise in their levels of SARS-CoV-2-targeting killer T cells.[3]<\/a><\/sup> <\/p>\n

Another study published in JAMA Internal Medicine found that treatment with nirmatrelvir during the acute phase of COVID-19 may reduce the risk for post-acute adverse health outcomes. The study included 35,717 veterans who had a severe acute respiratory syndrome coronavirus 2 positive test result between Jan. 3, 2022, and Dec. 31, 2022, with at least one risk factor for severe COVID-19 who were treated with oral nirmatrelvir within five days after the positive test.[4]<\/a><\/sup> <\/p>\n

In conclusion, the study highlights the importance of contextualizing information about COVID-19 vaccines and being transparent about their risk-benefit profiles to improve overall vaccine acceptance. Additionally, the study emphasizes the effectiveness of COVID-19 vaccines in reducing infection, morbidity, and mortality, even against the newest emerging COVID-19 variants. Finally, the study highlights the potential benefits of treatment with nirmatrelvir during the acute phase of COVID-19 in reducing the risk for post-acute adverse health outcomes.<\/p>\n

0. <\/span>“LinkUP intervention improves COVID-19 testing, vaccination referral rates among PWID” Healio, 27 Mar. 2023, https:\/\/www.healio.com\/news\/infectious-disease\/20230327\/linkup-intervention-improves-covid19-testing-vaccination-referral-rates-among-pwid<\/a><\/p>\n

1. <\/span>“Prior Experiences Shape Expectations of COVID-19 Vaccine Adverse Effects” Mirage News, 27 Mar. 2023, https:\/\/www.miragenews.com\/prior-experiences-shape-expectations-of-covid-975149\/<\/a><\/p>\n

2. <\/span>“Negative Expectations of COVID-19 Vaccines Led to More Adverse Events After Vaccination” Contagionlive.com, 28 Mar. 2023, https:\/\/www.contagionlive.com\/view\/negative-expectations-of-covid-19-vaccines-led-to-more-adverse-events-after-vaccination<\/a><\/p>\n

3. <\/span>“mRNA vaccine beats infection for key defense against COVID-19, Stanford Medicine scientists find” Stanford Medical Center Report, 28 Mar. 2023, https:\/\/med.stanford.edu\/news\/all-news\/2023\/03\/vaccine-covid-infection.html<\/a><\/p>\n

4. <\/span>“Nirmatrelvir Cuts Risk for Post-COVID-19 Condition | Health” Islander News.com, 27 Mar. 2023, https:\/\/www.islandernews.com\/lifestyle\/health\/nirmatrelvir-cuts-risk-for-post-covid-19-condition\/article_75f0e029-a0ac-5fa7-905a-0b924ffc6cd4.html<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

A recent study published in JAMA Network Open explored the relationship between pre-vaccination expectations and systemic adverse events among individuals receiving their second dose of a COVID-19 vaccine.[0] The study found that expectations of low benefit, high adverse effects, and prior negative experiences were associated with COVID-19 vaccination adverse effects. Additionally, the tendency to catastrophize […]<\/p>\n","protected":false},"author":2,"featured_media":203,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[],"_links":{"self":[{"href":"https:\/\/coco66.com\/wp-json\/wp\/v2\/posts\/204"}],"collection":[{"href":"https:\/\/coco66.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/coco66.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/coco66.com\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/coco66.com\/wp-json\/wp\/v2\/comments?post=204"}],"version-history":[{"count":1,"href":"https:\/\/coco66.com\/wp-json\/wp\/v2\/posts\/204\/revisions"}],"predecessor-version":[{"id":205,"href":"https:\/\/coco66.com\/wp-json\/wp\/v2\/posts\/204\/revisions\/205"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/coco66.com\/wp-json\/wp\/v2\/media\/203"}],"wp:attachment":[{"href":"https:\/\/coco66.com\/wp-json\/wp\/v2\/media?parent=204"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/coco66.com\/wp-json\/wp\/v2\/categories?post=204"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/coco66.com\/wp-json\/wp\/v2\/tags?post=204"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}